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Analytical Support Services
Working 24/7 to validate your chemistry
When you send PDS your chemistry work, you want to be assured that the allocated chemist(s) are fully focussed on the delivery of your chemistry. PDS achieves this through our “High Speed Delivery” process, a core element of which is our analytical support:
Synthetic chemists at PDS are supported by a specialist & fully dedicated analytical team which operates 24/7. PDS has dedicated analytical suites containing advanced analytical equipment and a team of over 55 analytical scientists (1 analytical scientist for every 6 chemists). The analytical team works closely with your chemists and takes charge for method development, preparative purification and characterization, allowing the chemists to target the trouble-shooting time and efficiency, on delivery of your chemistry.
Key Analytical Support services offered:
- Chiral purification-gram scale by Super Critical Fluid Chromatography (SFC)
- Prep HPLC Purification services
- Impurity isolation and characterization
- NMR analysis e.g. 1H NMR, 13C NMR, 2D experiments, 15N NMR, 31P NMR, 19F NMR
- Qualitative and quantitative analysis by HPLC
- LCMS analysis by using single quadruple Mass detector
The performance of our Analytical suites is monitored weekly and is bench marked against standards of leading organizations in our industry. We also have the capability to quickly add capacity if the project demands. In addition, we maintain service agreements with suppliers both in the UK and India for timely delivery and maintenance of each piece of equipment.
Key Analytical Equipments:
- Two Multi-probe,Variable Temperature High field NMRs
- 11 Preparative HPLCs
- 9 LCMs
- 7 HPLC
- Preparatory SFC 200 for isolation/ and purification
- SFC investigator for Chiral method development
A range of detectors, GCs, microwaves and other scientific equipment are available to your project team to enable high quality purification and analysis.
In-vitro ADME Service
Non-GMP Kilo lab
Analytical Support Services
Piramal Discovery Solutions (PDS) is a reputed service provider for mg to gm scale discovery chemistry. We have partnered with a range of well known pharmaceutical and biotechnology companies from Europe, USA and Japan.
In vitro facilities at PDS provide ADME (absorption, distribution, metabolism, excretion) services to provide faster and improved decision making points for our Chemistry clients or standalone offering to support drug discovery programs.
Piramal’s fully-equipped kilo-lab allows for rapid development of scalable and robust chemical processes using advanced process methodologies to provide a quick supply in the early phase of the development.