Various Pharmaceutical Dosage Forms

Drug Dosage Form Development

Piramal provides comprehensive Drug dosage form development and manufacturing services, catering to a wide variety of dosage forms including oral solids, liquids, creams, ointments, and sterile injectables. With our globally integrated network of facilities, we offer end-to-end manufacturing and fill/finish of antibody drug conjugates and other biologics. Our deep expertise across the entire product development and manufacturing lifecycle enables us to assist in selecting, crafting, and producing the ideal dosage form to meet your product requirements.

Formulation Services

Featured Services

Dosage forms of medications

Oral Solid Dosage Manufacturing & Development

Piramal brings extensive expertise to oral solid dosage manufacturing and development, offering phase-appropriate solutions to advance your drug seamlessly from early development to commercial production. 

Our capabilities encompass a broad range of oral solid forms, including conventional tablets, modified-release formulations, press-coated tablets, mini-tablets, and hard gelatin capsules. Whether developing formulations for new chemical entities (NCEs) or serving as a cost-effective partner for generic medicines, Piramal ensures quality and efficiency through its globally integrated network of facilities.

Dose Forms Handled

  • Tablets (Film-coated/IR/ER/MR)
  • Sublingual
  • Orally disintegrating tablets
  • Hard gelatin capsules (Powders, granules, and pellets)
  • Special solid dosage forms - Press coated tablets, bi-layer tablets, controlled release solids
  • Pediatric formulations

Process knowledge and expertise in solid dose operations

  • Setup for the development and manufacturing of potent oral solid formulations (OEL > 1ug/m3 )
  • Wet and dry granulation
  • Roller compaction
  • Fluid bed processing and drying
  • Compression and encapsulation
  • Film coating and tablet coating
  • Press coating technology
  • High-speed blister packaging and bottle packaging capability
  • Dedicated low RH block, can handle up to 20% RH
Pharmaceutical Liquids and cream tube

Liquid, Cream, and Ointment Development and Manufacturing Services

We offer liquid, cream and ointment development, manufacturing and packaging services from our Sellersville, USA facility. Owing to our rich experience, we are well-versed in the challenges associated with the development of liquid and semi-solid forms and are proficient in dealing with them to deliver the optimal dosage form for your drug.

Manufacturing Capabilities

  • Liquids:
    • 8 manufacturing suites
    • Potent suite &ndash 2 rooms
    • Floor scales in 3 suites
    • 10,000L bulk holding tanks equipped with 2 propellers & steam jacket capable
  • Creams and ointments:
    • 9 manufacturing suites and 7 main manufacturing tanks
    • Tanks equipped with counter rotating blades with side scrappers
    • High shear mixing tanks
    • Rooms capable of utilizing portable tanks
    • Bulk holding tanks
    • 1 Lydon dryer

Packaging Capabilities

  • Creams and ointments:
    • 15g-70g tube sizes
    • Norden tube filler - aluminium tubes/triple fold
    • Norden carton machine
    • Poster bundler
  • Large volume liquids:
    • 120ml &ndash 960ml bottle sizes (HDPE Bottles)
    • USB 15 Head Monoblock fill by weight filler
    • Label-Aire labeler
    • Hamrick drop packer
  • Small volume liquid:
    • 100ml &ndash 240 ml bottle sizes
    • Palace bottle unscramble
    • Capmatic &ndash monoblock XP filler
    • Label Star labeller with Cognex vision system
    • IWKA carton machine
  • Rectal suspension:
    • McBrady orbit bottle rinser
    • Sig Pack DoBoy (pouch sealer)
Sterile injectables manufacturing

Advanced Sterile Injectable Manufacturing

Our Lexington, USA facility specializes in sterile injectable manufacturing, offering cGMP production for a wide range of parenteral drug products in both liquid and lyophilized dosage forms.  

We combine personalized service with exceptional speed and flexibility to meet your unique needs. Utilizing unique mobile isolator technology, we ensure product containment for potent and cytotoxic compounds while maintaining an aseptic manufacturing environment, supporting seamless Sterile Fill/Finish operations.

Product Experience

  • Sterile Solutions and Suspensions (Aqueous/Non-aqueous)
  • In-situ Salt Formations
  • Nanoparticles and Liposomes
  • Stable emulsions
  • Lyophilized Products

Featured Services

  • Process Development and Optimization
  • Clinical and Commercial manufacturing of liquid and lyophilized formulations
  • Pre-Clinical to Phase III Manufacturing for:
    • Animal Safety/Toxicity Studies
    • Human Clinical Products
    • Veterinary Products
  • Development and manufacture of potent drug products
  • Pilot-Scale Manufacturing: Aseptic and Non-Aseptic
  • Sterile and ADC Fill/Finish:
    • Vials from 2 &ndash 50 mL
    • Dispensing volume as low as 0.5 mL up to 50 mL
    • Veterinary Products
  • Parenteral Liquids, creams and ointments:
    • Vials from 2 &ndash 50 mL
    • Dispensing volume as low as 0.5 mL up to 50 mL
  • Terminal Sterilization
  • Salient Features :
    • Class C (Class 10,000) formulation room
    • Class A (Class 100) biological safety cabinets in each formulation room
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Shanghai, China - Sourcing Office

Associate Company of Piramal Pharma Ltd.

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